Industry Development Partner
OncoImmunity is a bioinformatics company offering proprietary machine-learning based software to address the key knowledge gaps in the prediction of bone fide immunogenic neoantigens for personalized cancer immunotherapy. OncoImmunity is dedicated to develop software solutions that facilitate effective patient selection for cancer immunotherapy, and identify optimal neoantigen targets for truly personalised cancer vaccines & cell therapies in clinically actionable time-frame.
Adaptive Biotechnologies is a pioneer in combining high-throughput sequencing and expert bioinformatics to profile T-cell and B-cell receptors. Adaptive Therapeutics’ platform allows the discovery of potent, ultra-low frequency TCRs with differentiated therapeutic potential. This TruTCRTM engine combines Adaptive’s foundational immunosequencing platform with a multiplex approach to map TCRs to antigens at high specificity plus pairSEQTM to accurately pair TCR alpha/beta chains. Adaptive has discovered and is validating candidate TCRs with superior cytolytic activity in oncology.
Personalis, Inc. is a growing cancer genomics company transforming the development of next-generation therapies by providing more comprehensive molecular data about each patient’s cancer and immune response. The company’s NeXT™ Platform is designed to adapt to the complex and evolving understanding of cancer, providing its biopharmaceutical customers with information on all of the approximately 20,000 human genes, together with the immune system, from a single tissue sample. The Personalis Clinical Laboratory is GxP aligned as well as CLIA’88-certified and CAP-accredited. For more information, please visit www.personalis.com and follow Personalis on Twitter (@PersonalisInc).
The PolyPeptide Group employs approximately 750 staff at sites in Belgium, France, India, Sweden and the USA. The PolyPeptide Group is the world’s largest independent contract manufacturer of therapeutic peptides. The privately-held organization manufactures over one third of all approved peptide drug substances and accounts for over 30% of the sales of outsourced peptide therapeutics worldwide. The Group offers its customers an almost unprecedented long-term security of supply with six GMP facilities worldwide and an exclusive focus on pharmaceutical peptide manufacture.
Shenzhen Yuce Biotechnology (Yucebio) is a leading biotech company in China, focusing on neoantigen based tumor immune diagnosis and treatment. We provide a comprehensive solution for clinical unmet need and for potential drug target discovery. Yucebio is a member of TESLA (Tumor Epitope SeLection Alliance), our vision is making cancer immunotherapies more effective!
IOVaxis is an immunoncology company dedicated to research and development of neoantigen-based cancer immunotherapy including personalized therapeutic cancer vaccines. We are looking for clinical partners for our therapeutic cancer vaccines based on our “NeoCure” and “NeoReady” platforms.
The Liberty PRIME is the absolute best system available for synthesizing peptides for personalized medicine. The system is cGMP compliant with unmatched purity, speed, and efficiency for peptide production in batch quantities. No other peptide synthesizer even comes close to the PRIME’s incredibly fast cycle times, with absolute minimum waste production. CEM Corporation has pioneered the use of microwave technology for peptide production since 2004 and remains the market leader in peptide synthesis instrumentation.
Almac has been supplying peptides to the research community and for clinical trials for over 20 years. The field of personalized cancer vaccines requires a new manufacturing paradigm to ensure high throughput manufacture of multiple neoantigens in an appropriate timescale to the required quality and regulatory standards. Almac has created a unique offering to meet all of those demands, which can be tailored to meet specific client needs.
Bachem provides a full range of services to the pharma and biotech industries. It specializes in the development of innovative, efficient manufacturing processes and the reliable production of peptide-based active pharmaceutical ingredients. The group has a global reach with more experience and know-how than any other company in the industry. Towards its customers, Bachem shows total commitment to quality, innovation and partnership.
Bachem. Pioneering Partner for Peptides
Cayman Chemical’s Immunopeptidome Profiling Services enable efficient, cost-effective deep sequence analysis of MHC Class I and II associated peptides by LC-MS/MS, enabling neoantigen identification in cell lines and tumor tissue, and immunogenicity testing of biological therapeutics. Immunopeptidome Profiling is part of Cayman’s diverse suite of discovery services including medicinal chemistry, structure-based drug design, complex multi-step organic synthesis, analytical chemistry, bioanalysis, and custom assay development.
Caprion Biosciences is a specialty laboratory CRO with an established track record in biomarkers, bioanalytical and immune monitoring services. Through its advanced immune monitoring platform, Caprion supports the development of vaccine and immunotherapy programs that require the characterization of innate and adaptive immunity. With its combined expertise in immune monitoring and mass spectrometry, Caprion brings in-depth knowledge of analytical and regulatory requirements and a commitment to open and real-time collaboration.
CPC Scientific is a globally recognized and leading CDMO specializing in synthetic peptide production. We work directly with leaders in the biotechnology and pharmaceutical industries to help bring life-changing therapeutics and diagnostics to market. We boast the largest GMP peptide facility in the world, which successfully has undergone multiple FDA inspections and audits by global pharma organizations. CPC Scientific has the capability of serving customers from early drug discovery stages through clinical trials to commercial manufacturing.
A critical factor facing the Cell Therapy industry is choosing technologies and partners that can deliver scale. There’s no other field of medicine that requires the level of mass customization of production and careful orchestration of production pathways that cell therapies demand. From sample collection through logistics, manufacturing and final transplantation, TrakCel’s proven technology integrates and orchestrates every aspect of your Autologous and Allogeneic supply chains in a scalable, compliant and validated technology platform.