Industry Development Partner
NEC OncoImmunity is a bioinformatics company offering proprietary machine-learning based software to address the key knowledge gaps in the prediction of bone fide immunogenic neoantigens for personalized cancer immunotherapy. NEC OncoImmunity is dedicated to develop software solutions that facilitate effective patient selection for cancer immunotherapy, and identify optimal neoantigen targets for truly personalised cancer vaccines & cell therapies in clinically actionable time-frame.
Adaptive Biotechnologies is a pioneer in combining high-throughput sequencing and expert bioinformatics to profile T-cell and B-cell receptors. Adaptive Therapeutics’ platform allows the discovery of potent, ultra-low frequency TCRs with differentiated therapeutic potential. This TruTCRTM engine combines Adaptive’s foundational immunosequencing platform with a multiplex approach to map TCRs to antigens at high specificity plus pairSEQTM to accurately pair TCR alpha/beta chains. Adaptive has discovered and is validating candidate TCRs with superior cytolytic activity in oncology.
Personalis, Inc. is a growing cancer genomics company transforming the development of next-generation therapies by providing more comprehensive molecular data about each patient’s cancer and immune response. The company’s NeXT™ Platform is designed to adapt to the complex and evolving understanding of cancer, providing its biopharmaceutical customers with information on all of the approximately 20,000 human genes, together with the immune system, from a single tissue sample. The Personalis Clinical Laboratory is GxP aligned as well as CLIA’88-certified and CAP-accredited. For more information, please visit www.personalis.com and follow Personalis on Twitter (@PersonalisInc).
The PolyPeptide Group employs approximately 750 staff at sites in Belgium, France, India, Sweden and the USA. The PolyPeptide Group is the world’s largest independent contract manufacturer of therapeutic peptides. The privately-held organization manufactures over one third of all approved peptide drug substances and accounts for over 30% of the sales of outsourced peptide therapeutics worldwide. The Group offers its customers an almost unprecedented long-term security of supply with six GMP facilities worldwide and an exclusive focus on pharmaceutical peptide manufacture.
Cayman Chemical’s Immunopeptidome Profiling Services enable efficient, cost-effective deep sequence analysis of MHC Class I and II associated peptides by LC-MS/MS, enabling neoantigen identification in cell lines and tumor tissue, and immunogenicity testing of biological therapeutics. Immunopeptidome Profiling is part of Cayman’s diverse suite of discovery services including medicinal chemistry, structure-based drug design, complex multi-step organic synthesis, analytical chemistry, bioanalysis, and custom assay development.
GenScript Biotech Corporation (Stock Code: 1548.HK) is a global biotechnology group. GenScript’s businesses encompass four major categories based on its leading gene synthesis technology, including operation as a Life Science CRO (gene, peptide, protein, antibody services), enzyme and synthetic biology products, biologics development and manufacturing (Cell line development, leads discovery, leads generation and development), as well as cell therapy.
Gyros Protein Technologies AB is a leading provider of solutions for peptide synthesis and bioanalysis. Automated multi-channel peptide synthesizers from Gyros Protein Technologies are used in cGMP facilities for the rapid production of peptides for personalized medicine.
Our focus is on helping scientists in industry and academia to increase productivity in research, drug discovery, pre-clinical and clinical development. The company combines the nanoliter-scale immunoassay expertise of Gyros with over three decades of instrument manufacturing experience and scientific knowledge in peptide synthesis found in Protein Technologies.
BCN Peptides is completely focused on the cGMP manufacture of Bioactive Peptides for Pharmaceutical and Veterinary applications. We concentrate our efforts in the following activities:
• Synthesis of API Peptides.
• Production of Peptides for Personalized Medicine. Manufacturing of Small quantities of GMP Peptides devoted for a single patient. This is a new approach for API production, including GMP requirements and Regulatory requirements that require a new scenario for both Industry and Authorities.
Almac has been supplying peptides to the research community and for clinical trials for over 20 years. The field of personalized cancer vaccines requires a new manufacturing paradigm to ensure high throughput manufacture of multiple neoantigens in an appropriate timescale to the required quality and regulatory standards. Almac has created a unique offering to meet all of those demands, which can be tailored to meet specific client needs.
The Liberty PRIME is the absolute best system available for synthesizing peptides for personalized medicine. The system is cGMP compliant with unmatched purity, speed, and efficiency for peptide production in batch quantities. No other peptide synthesizer even comes close to the PRIME’s incredibly fast cycle times, with absolute minimum waste production. CEM Corporation has pioneered the use of microwave technology for peptide production since 2004 and remains the market leader in peptide synthesis instrumentation.
Caprion Biosciences, a CRO laboratory, helps advance biomarker research through scientific partnership and innovative technologies. Our platforms include large-scale proteomic profiling using quantitative mass spectrometry, multi-parametric flow cytometry (peripheral blood and TILs), cytokine testing and ELISpot for monitoring of complex innate and adaptive immune responses. Through a unique approach, we provide discovery and characterization of tumor antigens and neo-epitopes. Our team of expert draws on deep understanding and years of experience in immuno-oncology and immunology.