Identification of Novel pHLA Targets for Solid Tumor Targeting With Cancer Vaccines

Time: 5:30 pm
day: Day One


• Advantages of intracellular targets (pHLAs) versus viral, neoantigens or conventional cell surface antigens
• Strategies to find the most prevalent and immunogenic pHLA targets in tumors from CPI responders
• Selection of self-antigen targets with highest tumor vs normal ratios to avoid off-tumor, on-target toxicities